Adjuvant Systems

Your partner for modern vaccine development. Our unique GMP portfolio and outstanding expertise can meet your adjuvant needs. Collaborate with our scientists to create the vaccines of tomorrow.

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View all adjuvants

Your adjuvant development partner

We support you with the adjuvant solution for your vaccine needs

We are an industry leader in human and veterinary vaccine adjuvants. Leveraging over 80 years of expertise, our collaborations start at all stages of the vaccine manufacturing process. Our comprehensive portfolio of components accelerates the production of complete adjuvant systems.

Let's create a tailored vaccine solution together.

Leading source of next-generation adjuvants

Vaccines save countless lives. We can protect even more people by building the vaccines of the future. This is only possible if we unveil new adjuvant options.

We support you with immunostimulators and adjuvant systems that fulfill the needs of your vaccines. We're partnering with world-leading scientists to unlock novel technologies. Together, we can create breakthroughs in prophylactic and therapeutic vaccine development. Our unique supply capabilities can support you from early research to large-scale, commercial production. Capitalise on our diverse portfolio and breadth of knowledge to bring the next generation of safe and effective vaccines into the world.

Empowering the development of tomorrow's vaccines

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Sustainable Squalene

Our sustainable Squalene is based on cutting-edge technology using synthetic biology to obtain squalene from a fermentation process.

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PHAD™ (MPLA Analogue)

Versatile and effective, PHAD acts as a TLR4 agonist to activate proinflammatory cytokines and antigen-specific effector cells. PHAD is the first synthetic analogue of monophosphoryl lipid A (MPLA), also...

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CAF01®

Part of our new generation of adjuvants, CAF01 is a liposomal adjuvant formulation that offers excellent long-term stability and drives both humoral and cellular immune responses.

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CAF09b®

A novel liposomal adjuvant used in cancer immunotherapy trials, CAF09b has the capacity to facilitate the production of CD8+ T-cells.

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Adju-Phos™

Well-established as a common component in a variety of vaccines, Adju-Phos is an aluminium-based adjuvant that induces strong Th2 immune responses.

3D(6-acyl)-PHAD™

Immunostimulatory and highly purified, 3D(6-acyl)-PHAD activates TLR4 to induce proinflammatory cytokines and T-cells. 3D(6-acyl)-PHAD is a synthetically produced structural analogue of monophosphoryl...

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3D-PHAD™

Highly pure, safe, and chemically stable, 3D-PHAD stimulates the immune system through the activation of TLR4, leading to the production of proinflammatory cytokines, CD4+ and CD8+ T-cells. 3D-PHAD is...

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Alhydrogel™

One of the most widely used vaccine adjuvants, Alhydrogel is an aluminium-based adjuvant used in clinically-approved vaccines that can elicit effective Th2 immune responses.

QS 21

A powerful immunostimulatory saponin that acts as a potent vaccine adjuvant, QS 21 can stimulate both cell-mediated (Th1) and humoral (Th2) immune responses

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Quil-A™

A versatile immunostimulatory saponin that’s widely used as a potent veterinary adjuvant, Quil-A can work against both intra- and extra-cellular pathogens, stimulating innate and Th-mediated adaptive immune...

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What are adjuvants?

Adjuvants have been used for decades to help enhance the immune response to vaccine antigens. Most of us understand the fundamentals of vaccines: introduce part of a pathogen to our immune system, in order to elicit a specific, lasting immune response that protects us from a future infection. Adjuvants are vaccine ingredients that can help induce a strong immune response in certain formulations. Today, aluminium salts are the most widely used adjuvants, whilst scientists and vaccine manufacturers are continuously innovating to expand the repertoire of available adjuvant options.

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Vaccine delivery systems

What you add to a vaccine can make it more potent. Our selection of aluminium-based and liposomal adjuvants, such as our newly available CAF range, can help improve the effectiveness of your vaccine formulations.

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Immunostimulators

Stimulation of the immune response is crucial in offering pathogen protection. Our range of pattern recognition receptor agonists (TLR, CLR, etc) and saponins act as immunostimulatory agents to enhance the immune response, and therefore support the efficacy of your vaccine formulations.

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Formulation compounds for delivery

Purity is an incredibly important factor for successful vaccine development. Our Super Refined excipients are ultra purified to remove impurities that are commonly found in standard compendial grade excipients, optimising the performance of pharmaceutical formulations.

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Exceptional standards in adjuvant manufacturing

Our aseptic process ensures we can deliver sterile aluminium according to GMP EudraLex Volume 4. We are one of the only companies worldwide to operate at such premium standards. Our Quality Management System is continually improved through established metrics.

A history of supporting vaccines

As a key player in adjuvant development since 1939, our adjuvants have consistently been featured in countless peer-reviewed papers. Our leading R&D capabilities demonstrate our determination to advance drug delivery systems and novel vaccine adjuvants to tackle even more pathogens.

Dedicated to your vaccine success

Developing and manufacturing vaccines is a costly challenge. Our team of experts are committed to helping you choose the right adjuvant for your needs. Save time and money by leveraging our decades worth of experience.

Download our vaccines brochure here:

Empowering the development of tomorrow's vaccines

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Adjuvant Systems

Your adjuvant development partner

We support you with the adjuvant solution for your vaccine needs

Leading source of next-generation adjuvants

Empowering the development of tomorrow's vaccines

Sustainable Squalene

PHAD™ (MPLA Analogue)

CAF01®

CAF09b®

Adju-Phos™

3D(6-acyl)-PHAD™

3D-PHAD™

Alhydrogel™

QS 21

Quil-A™

What are adjuvants?

Vaccine delivery systems

Immunostimulators

Formulation compounds for delivery

Exceptional standards in adjuvant manufacturing

A history of supporting vaccines

Dedicated to your vaccine success

Download our vaccines brochure here:

Supporting Literature

Empowering the development of tomorrow's vaccines

EXCLUSIVE WHITEPAPER: Vaccines for a more sustainable future

Discover our drug delivery platforms

Contact our experts today