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Well-established as a common component in a variety of vaccines, Adju-Phos is an aluminium-based adjuvant that induces strong Th2 immune responses.

Adju-Phos is our aluminium phosphate gel that has been specifically developed for use as an adjuvant in vaccines. Adju-Phos has a net negative charge at neutral pH and effectively adsorbs positively charged antigens. Adju-Phos differentiates itself from Alhydrogel both chemically and structurally, both being amorphous aggregates of nanometre-size hydrous crystallites.

Like Alhydrogel, Adju-Phos primarily stimulates a Th2-mediated humoral response and can be combined with other adjuvants (such as monophosphoryl lipid-A and analogues) to imprint a different immune fingerprint, in the case of monophosphoryl lipid-A, a stronger and more balanced Th1/Th2 response.

Aluminium adjuvants are used in human vaccines for tetanus, diphtheria, pertussis, poliomyelitis, as well as hepatitis A and B.

We are the only global provider to offer aluminium-based adjuvants to such a high standard. Let us help you fulfil your adjuvant needs.

Adju-Phos is a registered trademark of Croda International Plc.

Product details

Chemical group

  • Aluminium hydroxyphosphate

Administration route

  • Vaccine adjuvant

Market application

  • Human vaccines
  • Veterinary vaccines


  • Vaccine adjuvant

Physical form

  • A gel-like aqueous suspension. A supernatant forms when the product is left idle.
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cGMP manufacturing

We offer sterile and aseptically filled aluminium-based adjuvants. Our site in Denmark is a certified cGMP manufacturing plant. It is approved by the Danish Medicines Agency for the manufacture of sterile and aseptically filled intermediates in accordance with EU GMP Part 1 (Basic Requirements for Medicinal Products) and Annexe 1 (Manufacture of Sterile Medicinal Products).