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Excipients for Small Molecule Delivery

We offer high purity, multi-compendial, pharmaceutical excipients for small molecule drug delivery. Our portfolio of high purity excipient products and speciality chemistries solve formulation challenges and enhance drug delivery across a variety of administration routes and dosage forms.

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Your Small Molecule Delivery partner

High purity excipients for Small Molecule Delivery

We believe in an approachable way of working – providing you with direct access to our technical teams and customer support; Enabling faster communication and collaboration with ease, as well as supporting the development of innovative formulations. Our analytical capabilities support formulation development and improve formulation performance, allowing you to optimise your drug delivery system.

We aim to grow and outperform in the market sectors we serve through staying attentive to our customer’s needs and using our technical and manufacturing expertise.

Our offering in Small Molecule Delivery

We are market leaders as the exclusive supplier of Super Refined™ excipients, specifically developed to optimise API stability and improve the performance of your  pharmaceutical formulations, aiding in the manufacture of: 

  • Small molecule parenterals
  • Topicals
  • Ophthalmic and inhalation.

Super Refined™ pharmaceutical excipients

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Pharmaceutical excipients for ophthalmic formulations

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Super Refined™ excipients for parenteral drug delivery

Super refined excipients for parenteral drug delivery brochure
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Super Refined™ excipients for Small Molecule Delivery

Formulation challenges are not uncommon in pharmaceutical formulation, frequent challenges include the use of highly unstable APIs and excipient-drug interaction. 

Our Croda experts have designed our Super Refined™ excipients to combat formulation challenges and to provide additional value to your final drug product. Our range of emulsifiers, permeation enhancers, emollients and solvents enhance stability and have a variety of formulation benefits including:

  • Minimised API degradation
  • Reduced impurity profiles for improved drug compatibility
  • Reduced oxidation potential for increased drug stability
  • Batch-to-batch consistency.

Together these benefits can add value to your final drug product through optimised drug efficacy, increased shelf life, decreased time to market, and increased patient comfort. Get in touch with one of our technical experts today to discuss your formulation needs and discover how our Super Refined ™ range can benefit you.

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Super Refined™ excipients

Our Super refined™ range of excipients ensure your formulations are stable, effective and consistent.

We offer high purity, multi-compendial, pharmaceutical excipients for small molecule drug delivery. Our portfolio of high purity excipient products and speciality chemistries solve formulation challenges and enhance drug delivery across a variety of administration routes and dosage forms.

Super Refined™ excipients

Super Refined excipients are stripped of a number of oxidative impurities, such as peroxides, aldehydes, and catalyst residues. The removal of these problematic species helps to reduce negative API & excipient interactions, maintaining both the stability of the drug and the final formulation. In addition, the removal of these impurities can minimise cellular irritation, reduce taste impact, and potentially decrease allergenicity. 

We have a large variety of products, ranging from various polysorbates, polyethylene glycols (PEG), esters, vegetable oils, and more. 
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Add significant value to your drug formulations today with our Super Refined™ range offering:

icon graphic for api degradation

Minimised API degradation


Reduced oxidation potential

Reduced impurities

Reduced impurities and allergic potential

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Ophthalmic drug delivery

Our high purity excipients for ophthalmic drug delivery empower the formulation of breakthrough mAb and gene therapies for the treatment of retinal disease and other rare, orphan eye diseases. By accelerating the drug development process, we allow therapies to reach patients sooner.

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Oral drug delivery

Oral drug development of both new and existing chemical entities often face numerous challenges including poor solubility, formulation instability and ineffective drug delivery. Regardless of the challenge, the ultimate goal is to create successful drug products with shortened development timelines. The selection of the right oral excipient during early phase development is critical to achieve this goal.

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Parenteral drug delivery

Parenteral and injectable dosage forms pose unique challenges in comparison to other administration routes. While systemic administration offers advantages in terms of absorption and the elimination of first pass metabolism, these benefits are associated with challenges too. Parental formulation frequently faces limitations associated with drug stability and poor solubility. Drug compatibility and the minimum concentration of drug required to produce the targeted pharmacological effect are key to excipient selection.

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Topical drug delivery

Our extensive experience in skin science has led to the development of innovative ingredients that enhance the efficacy and patient perception of topical pharmaceuticals. Our topical excipients include drug delivery systems, skin penetration enhancers, solubilisers, emulsifiers and emollients.

Penetration enhancer

Transdermal drug delivery

Our Super Refined™ excipients ensure that your formulation is stable, effective, and consistent, and thanks to their high purity they also have a reduced skin irritation effect, compared to standard grade excipients.