Your Small Molecule Delivery partner
High purity excipients for Small Molecule Delivery
We believe in an approachable way of working – providing you with direct access to our technical teams and customer support; Enabling faster communication and collaboration with ease, as well as supporting the development of innovative formulations. Our analytical capabilities support formulation development and improve formulation performance, allowing you to optimise your drug delivery system.
We aim to grow and outperform in the market sectors we serve through staying attentive to our customer’s needs and using our technical and manufacturing expertise.
Our offering in Small Molecule Delivery
We are market leaders as the exclusive supplier of Super Refined™ excipients, specifically developed to optimise API stability and improve the performance of your pharmaceutical formulations, aiding in the manufacture of:
- Small molecule parenterals
- Topicals
- Ophthalmic and inhalation.
From Lab to Patient: Optimising Oncology Formulations with Purified Excipients
Watch our on demand webinar to discover the impact of highly purified, Super Refined™ excipients on the stability and performance of several well-known small molecule chemotherapeutic formulations.
Injectable delivery of small molecules
Discover our vast portfolio of parenteral offerings used specifically in the injectable delivery of small molecules.
One category of our injectable excipient portfolio includes lipids. Lipid excipients play a pivotal role in enhancing the parenteral delivery of small molecule APIs by facilitating the formation of liposomes. Liposomes provide a stable and biocompatible carrier system for the encapsulation and solubilization of both hydrophobic and hydrophilic drug compounds. This unique capability not only improves the drug's bioavailability but also ensures a controlled and sustained release, optimizing therapeutic outcomes.
Liposomal drug delivery has shown proven efficacy in various small molecule applications, including pain management drugs as well as cancer therapies. The ability of liposomes to encapsulate drugs makes them an ideal choice for targeted delivery, addressing the specific challenges associated with these critical therapeutic areas. Our dedicated focus on developing cutting-edge lipid excipients underscores our commitment to advancing the field of injectable drug delivery, providing pharmaceutical developers with reliable solutions for formulating next-generation small molecule drugs.
Super Refined™ excipients for Small Molecule Delivery
Formulation challenges are not uncommon in pharmaceutical formulation, frequent challenges include the use of highly unstable APIs and excipient-drug interaction.
Our Croda experts have designed our Super Refined™ excipients to combat formulation challenges and to provide additional value to your final drug product. Our range of emulsifiers, permeation enhancers, emollients and solvents enhance stability and have a variety of formulation benefits including:
- Minimised API degradation
- Reduced impurity profiles for improved drug compatibility
- Reduced oxidation potential for increased drug stability
- Batch-to-batch consistency.
Together these benefits can add value to your final drug product through optimised drug efficacy, increased shelf life, decreased time to market, and increased patient comfort. Get in touch with one of our technical experts today to discuss your formulation needs and discover how our
Super Refined ™ range can benefit you.
Super Refined™ excipients
Our Super refined™ range of excipients ensure your formulations are stable, effective and consistent.
Add significant value to your drug formulations today with our Super Refined™ range offering:
Super Refined™ Polysorbate 20
Super Refining removes impurities, preventing adverse interactions with APIs and enhancing the stability of pharmaceutical formulations. Super Refined Polysorbates offer the complete solution when formulating...
Super Refined™ Polysorbate 80
Super Refined Polysorbates solubilise and stabilise the most sensitive active ingredients across dosage forms including injectable and oral.
Super Refining removes impurities (including primary and secondary...
Super Refined™ PEG 300
The Super Refined PEG range is a series of Super Refined polyethylene glycols, offering pharmaceutical formulators highly purified hydrophilic excipients that can enhance active and formulation stability....
Super Refined™ PEG 400
The Super Refined PEG range is a series of Super Refined polyethylene glycols, offering pharmaceutical formulators highly purified hydrophilic excipients that can enhance active and formulation stability....
Super Refined™ excipients
Super Refined excipients are stripped of a number of oxidative impurities, such as peroxides, aldehydes, and catalyst residues. The removal of these problematic species helps to reduce negative API & excipient interactions, maintaining both the stability of the drug and the final formulation. In addition, the removal of these impurities can minimise cellular irritation, reduce taste impact, and potentially decrease allergenicity.
We have a large variety of products, ranging from various polysorbates, polyethylene glycols (PEG), esters, vegetable oils, and more.
Tell me more
We have a large variety of products, ranging from various polysorbates, polyethylene glycols (PEG), esters, vegetable oils, and more.