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Pharma - Consumer Health

Transdermal drug delivery

Our range of excipients are multicompendial and meet standards of international pharmacopoeias. Our products offer batch to batch consistency and our global manufacturing infrastructure, expert regulatory support and application know-how make us the partner of choice!

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Super Refined™ solutions for transdermal drug delivery systems

Transdermal drug delivery systems (TDDS) deliver specific doses of medication through the skin into the systemic circulation for therapeutic effects. TDDS is a non-invasive, painless method of delivering drugs, by applying a drug formulation onto intact and healthy skin and has recently emerged as an alternative to conventional needle injections. Benefits include ease of administration, convenience, and persistence amongst patients. 

Our Super Refined™ excipients ensure that your formulation is stable, effective, and consistent, and thanks to their high purity they also have a reduced skin irritation effect, compared to standard grade excipients.

Advantages of transdermal delivery systems

  • Controlled release
  • Improved drug bioavaiability
  • Self-administration and reduced dosing frequency
  • Minimises adverse effects and easy to terminate
  • Suited for lipholic active pharmaceutical ingredient (API).

Disadvantages of transdermal delivery systems

  • Possibility of local skin irritation
  • Use of multiple patches can lead to medication error.
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Consumer Health

Our main goal in Consumer Health is to help our customers market consumer relevant label claims that grow their product and brand authority. We combine our technical expertise with regulatory knowledge to help our customers market innovative products.

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Transdermal excipient selection criteria

- Selection of patch design

- Solubility between API and excipient blend

- Physical and chemical compatibility between API and excipient blend

- Impact of excipient blend on skin permeation

- Impact of excipient blend on non-drug substance related impurities

- Impact of excipients on adherence for duration of wear period.

Our range of excipients are multicompendial and meet standards of international pharmacopoeias. Our products offer batch to batch consistency and our global manufacturing infrastructure, expert regulatory support and application know-how make us the partner of choice!

How our high purity excipients can help

- Excellent API solubility

- Excellent oxidation stability

- Excellent hydrolysis stability

- Low cellular irritation

- Better skin permeation enhancement

- Reduced odour impact.

Our range of excipients are multicompendial and meet standards of international pharmacopoeias. Our products offer batch to batch consistency and our global manufacturing infrastructure, expert regulatory support and application know-how make us the partner of choice! We help our customers formulate medicines with claims relevant to their customers, increasing the superiority of their product and brand.

Product benefits and claims

Our range of excipients are multicompendial and meet standards of international pharmacopoeias. Our products offer batch to batch consistency and our global manufacturing infrastructure, expert regulatory support and application know-how make us the partner of choice!

We help our customers formulate medicines with claims relevant to their customers, increasing the superiority of their product and brand. 

Product recommendations

13 items available

Consumer Health, transdermal drug delivery case study for muscle pain and tendinopathy: I want fast acting, long lasting pain relief which i can barely notice wearing

Several excipients in combination were required to achieve high drug solubility for a long lasting effect, the drug was prone to oxidation in excipients and some key solubilising excipients have a strong unpleasant odour.

Super Refined™ PEG 400, Super Refined Castor Oil and Crodamol™ DA Pharma offer the API solubility required when combined. Crodamol DA Pharma is low in odour compared to competitor diisopropyl adipate. Super Refined Polysorbate 80 helps compatibilise the formulation excipients. Our Super Refined excipients and Crodamol DA Pharma have superior stability, protecting the formulation from drug degradation.

Pack claims unlocked: - 1: Odourless, 2: Fast acting pain relief, 3: Less frequent application.

Contact our experts today

Croda Pharma is a world leader in pharmaceutical excipients, vaccine adjuvants and innovative lipids for human and veterinary applications. Get in touch with our experts today to get your next project started.
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