Prime effective immune responses
Elicit an amplified immune response through specific antigen presentation
Immunostimulators directly influence the immune response. Your selection of immunostimulators will direct the type of immune response. For example, whether the resultant response will be Th1, Th2, Th17 or T-cell mediated immunity.
As a result, they can play important roles in vaccine development by defining the type of immunity obtained (the immune fingerprint).
EXCLUSIVE WHITEPAPER: Vaccines for a more sustainable future
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![Toll-like receptor (TLR) agonists are a class of proteins that play fundamental roles in innate immunity. Their discovery was honoured with the 2011 Nobel Prize. By mimicking the structure of pathogens, they can help stimulate the immune system. They are known as excellent adjuvant targets, having been part of several approved vaccines, such as for cervical cancer, shingles and Hepatitis B.](/mediaassets/images/health-care/health-care-new-website/adjuvants-brochure/adjuvant-systems/shutterstock-313800779.png?h=538&iar=0&w=768&la=en-GB&hash=98CC5B2EB67BDD53C93A50FDCF35BD1E)
TLR agonists
Toll-like receptors (TLRs) are a class of proteins that play fundamental roles in innate immunity. They are known as excellent adjuvant targets, having been part of several approved vaccines, such as for cervical cancer, shingles and Hepatitis B. Their discovery was honoured with the 2011 Nobel Prize. By mimicking the structure of pathogens, different compounds acting as TLR agonists can help stimulate the immune system.
![Derived from the bark of Quillaja saponaria Molina, these natural glycosides can act as potent adjuvants. Their unique ability to stimulate Th1 immune responses and the production of cytotoxic T-cells makes them valuable vaccine adjuvant candidates for both human and veterinary purposes.](/mediaassets/images/health-care/health-care-new-website/adjuvants-brochure/adjuvant-systems/shutterstock-1643947495-bw.jpg?h=443&iar=0&w=768&la=en-GB&hash=B190A82C63D7E711D786142B179C715B)
Saponins
![QS_1_21](/croda_image_downloads.ashx?fn=Healthcare_0_shutterstock-2024372996.png&mn=healthcare&w=768&xr=0&yr=0&xfp=6&yfp=6&hash=EF9D0D2B05958E9070936AA86150810619C138999FEC74AA)
Featured
QS 21
A powerful immunostimulatory saponin that acts as a potent vaccine adjuvant, QS 21 can stimulate both cell-mediated (Th1) and humoral (Th2) immune responses
![Quil-A](/croda_image_downloads.ashx?fn=Healthcare_0_shutterstock_292091861.jpg&mn=healthcare&w=768&xr=0&yr=0&xfp=6&yfp=6&hash=1A793EFAA2D3D31BC2311028F826D22F19C138999FEC74AA)
Featured
Quil-A
A versatile immunostimulatory saponin that’s widely used as a potent veterinary adjuvant, Quil-A can work against both intra- and extra-cellular pathogens, stimulating innate and Th-mediated adaptive...
![Our aseptic process ensures we can deliver sterile aluminium according to GMP EudraLex Volume 4. We are one of the only companies worldwide to operate at such premium standards. Our Quality Management System is continually improved through established metrics.](/mediaassets/images/health-care/health-care-new-website/adjuvants-brochure/adjuvant-systems/dsc00382.jpg?h=512&iar=0&w=768&la=en-GB&hash=2FFF3517A6E6565C05CD6A6B940DE4D5)
Exceptional standards in adjuvant manufacturing
![As a key player in adjuvant development since 1939, our adjuvants have consistently been featured in countless peer-reviewed papers. Our leading R&D capabilities demonstrate our determination to advance drug delivery systems and novel vaccine adjuvants to tackle even more pathogens.](/mediaassets/images/health-care/health-care-new-website/adjuvants-brochure/adjuvant-systems/shutterstock-1767084407-general-filter.jpg?h=512&iar=0&w=768&la=en-GB&hash=3662F57E878AEA4FCC0BA9E925739FA8)
A history of supporting vaccines
![Developing and manufacturing vaccines is a costly challenge. Our team of experts are committed to helping you choose the right adjuvant for your needs. Save time and money by leveraging our decades worth of experience.](/mediaassets/images/health-care/health-care-new-website/adjuvants-brochure/adjuvant-systems/shutterstock-1190430574.jpg?h=512&iar=0&w=768&la=en-GB&hash=44DCE8333A97E2E21A1BF6B4223F2F98)
Dedicated to your vaccine success
Download our adjuvants brochure here:
Supporting Literature
Addressing the challenges of vaccine formulation
![Addressing the challenges of vaccine formulation brochure by Croda Pharma](/mediaassets/images/health-care/health-care-new-website/literature/addressing-the-challenges-of-vaccine-formulation.jpg?w=500&la=en-GB&focalpointcrop=1&xratio=105&yratio=140&hash=B007FD5DD11A71B98FB628124DA407AC)
EXCLUSIVE WHITEPAPER: Vaccines for a more sustainable future
![Download Croda Pharmas new whitepaper, Vaccines for a sustainable future](/mediaassets/images/health-care/health-care-new-website/literature/vaccines-for-a-sustainable-future-snippet.jpg?w=500&la=en-GB&focalpointcrop=1&xratio=105&yratio=140&hash=A411BC44762E8A72042F6548F81A6BDD)