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Immunostimulators

Priming the immune system through the use of tailored immunostimulators is an important component of vaccine development. Discover what selection works best for you.

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Prime effective immune responses

Elicit an amplified immune response through specific antigen presentation

Immunostimulators directly influence the immune response. Your selection of immunostimulators will direct the type of immune response. For example, whether the resultant response will be Th1, Th2, Th17 or T-cell mediated immunity.

As a result, they can play important roles in vaccine development by defining the type of immunity obtained (the immune fingerprint).

Explore our range of immunostimulators to fulfil your vaccine's immune correlates of protection.

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Toll-like receptor (TLR) agonists are a class of proteins that play fundamental roles in innate immunity. Their discovery was honoured with the 2011 Nobel Prize. By mimicking the structure of pathogens, they can help stimulate the immune system. They are known as excellent adjuvant targets, having been part of several approved vaccines, such as for cervical cancer, shingles and Hepatitis B.

TLR agonists

Toll-like receptor (TLR) agonists are a class of proteins that play fundamental roles in innate immunity. Their discovery was honoured with the 2011 Nobel Prize. By mimicking the structure of pathogens, they can help stimulate the immune system. They are known as excellent adjuvant targets, having been part of several approved vaccines, such as for cervical cancer, shingles and Hepatitis B.

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Derived from the bark of Quillaja saponaria Molina, these natural glycosides can act as potent adjuvants. Their unique ability to stimulate Th1 immune responses and the production of cytotoxic T-cells makes them valuable vaccine adjuvant candidates for both human and veterinary purposes.

Saponins

Derived from the bark of Quillaja saponaria Molina, these natural glycosides can act as potent adjuvants. Their unique ability to stimulate Th1 immune responses and the production of cytotoxic T-cells makes them valuable vaccine adjuvant candidates for both human and veterinary purposes.
QS_1_21

QS 21

A powerful immunostimulatory saponin that acts as a potent vaccine adjuvant, QS 21 can stimulate both cell-mediated (Th1) and humoral (Th2) immune responses

Quil-A

Quil-A™

A versatile immunostimulatory saponin that’s widely used as a potent veterinary adjuvant, Quil-A can work against both intra- and extra-cellular pathogens, stimulating innate and Th-mediated adaptive...

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Our aseptic process ensures we can deliver sterile aluminium according to GMP EudraLex Volume 4. We are one of the only companies worldwide to operate at such premium standards. Our Quality Management System is continually improved through established metrics.

Exceptional standards in adjuvant manufacturing

Our aseptic process ensures we can deliver sterile aluminium according to GMP EudraLex Volume 4. We are one of the only companies worldwide to operate at such premium standards. Our Quality Management System is continually improved through established metrics.
As a key player in adjuvant development since 1939, our adjuvants have consistently been featured in countless peer-reviewed papers. Our leading R&D capabilities demonstrate our determination to advance drug delivery systems and novel vaccine adjuvants to tackle even more pathogens.

A history of supporting vaccines

As a key player in adjuvant development since 1939, our adjuvants have consistently been featured in countless peer-reviewed papers. Our leading R&D capabilities demonstrate our determination to advance drug delivery systems and novel vaccine adjuvants to tackle even more pathogens.
Developing and manufacturing vaccines is a costly challenge. Our team of experts are committed to helping you choose the right adjuvant for your needs. Save time and money by leveraging our decades worth of experience.

Dedicated to your vaccine success

Developing and manufacturing vaccines is a costly challenge. Our team of experts are committed to helping you choose the right adjuvant for your needs. Save time and money by leveraging our decades worth of experience.

Download our adjuvants brochure here:

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Addressing the challenges of vaccine formulation brochure by Croda Pharma

Addressing the challenges of vaccine formulation

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