Functionalised lipids
Covalently linking drugs to PEGylated lipids containing disulfide, ester, carboxy, hydrazone, and other functional groups has been found to be a viable strategy to control drug loading and release. In addition, lipids functionalised with maleimide, NHS esters, DBCO, and others can be used enhance the lipid delivery system’s ability to deliver drug payloads to the intended therapeutic target through bioconjugation of antibodies, aptamers, peptides, proteins, and enzymes.
As innovation occurs in delivery formulations, Avanti is the perfect partner to supply the lipids to make your project a success! Our team of formulation and lipid synthesis experts are here to innovate with you and tackle challenges head on. Can’t find your perfect functionalised lipid? Contact our custom synthesis team today!
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Why partner with us?
Support from concept to commercial
It starts with having the leading lipid technology experts in synthesis and formulation and approaching the discovery process in a collaborative nature, then having the expertise to transfer those learnings into a GMP manufacturing environment to support clinical development. And finally, having the commercial production capability to support launch and commercial supply.
Our full range of services include process chemistry, scale-up manufacturing, supply chain management with analytical and regulatory requirements. Our experienced staff of chemists and lipid analysts are ready to meet your development needs with pre-clinical through phase III and commercial launch, speak to one of our experts today!
Lipid supporting services
Reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730700/