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Explore BioXPro™, our multi-compendial cGMP amino acids offering with ultra-low levels of metals and endotoxin

Unlocking efficiency and quality in biomanufacturing

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High purity amino acids for bioprocessing and formulation

Amino acids are the fundamental building blocks of proteins and play a critical role in various bioprocessing applications. From cell culture media to protein formulation, the selection and management of amino acids are central to driving efficiency, yield, and product quality in the biomanufacturing industry.

Explore BioXPro™ Amino Acids

Croda’s multi-compendial cGMP amino acids offer ultra-low levels of metals and endotoxin that reduces any potential variation in performance, resulting in high quality and improved batch-to-batch consistency for a range of pharmaceutical applications. 

Explore high purity amino acids for bioprocessing and formulation:

4 items available

bioxpro_1_arginine New

BioXPro™ Arginine

BioXPro™ Arginine is a high purity, low metals and low endotoxin L-arginine amino acid.
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BioXPro™ Arginine Hydrochloride

BioXPro™ Arginine Hydrochloride is a high purity, low metals and low endotoxin L-arginine amino acid salt.
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BioXPro™ Histidine

BioXPro™ Histidine is a high purity, low metals and low endotoxin L-histidine amino acid.
bioxpro_1_histidine_1_hydrochloride

BioXPro™ Histidine Hydrochloride

BioXPro™ Histidine Hydrochloride is a high purity, low metals and low endotoxin L-histidine amino acid salt.

Role of amino acids in bioprocessing

  • Cell culture media: Amino acids are vital ingredients in cell culture media, providing nutrients for the proliferation and maintenance of mammalian, microbial, and insect cell lines.
  • Protein expression: Supplementing the right balance of amino acids enhances recombinant protein expression, ensuring proper folding and biological activity.
  • Metabolic regulation: Amino acids influence cell metabolism, affecting by-product formation, cell viability, and process robustness.
  • Product quality: The profile and concentration of amino acids can impact glycosylation patterns and other critical quality attributes of biopharmaceuticals
  • Downstream purification: Amino acids can offer milder alternatives in protein washing steps and viral inactivation, improved separation in polishing and enhanced protein solubilisation and refolding.