Prime effective immune responses
Elicit an amplified immune response through specific antigen presentation
Immunostimulators directly influence the immune response. Your selection of immunostimulators will direct the type of immune response. For example, whether the resultant response will be Th1, Th2, Th17 or T-cell mediated immunity.
As a result, they can play important roles in vaccine development by defining the type of immunity obtained (the immune fingerprint).
Vaccines for a more sustainable future
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TLR agonists
Toll-like receptor (TLR) agonists are a class of proteins that play fundamental roles in innate immunity. Their discovery was honoured with the 2011 Nobel Prize. By mimicking the structure of pathogens, they can help stimulate the immune system. They are known as excellent adjuvant targets, having been part of several approved vaccines, such as for cervical cancer, shingles and Hepatitis B.
PHAD™ (MPLA Analogue)
PHAD actúa como un agonista del receptor Toll-like 4 (TLR4) versátil y eficaz para activar las citocinas proinflamatorias y las células efectoras específicas de antígeno.
3D-PHAD™
Puro, seguro y químicamente estable, 3D-PHAD estimula el sistema inmunitario a través de la activación de los receptores TLR4, lo que lleva a la producción de citoquinas proinflamatorias, células T CD4+...
3D(6-acyl)-PHAD™
3D(6-acyl)-PHAD actúa como un inmunoestimulante altamente purificado ya que activa las células TLR4 para la inducción de citocinas proinflamatorias y células T.
Saponins
Derived from the bark of Quillaja saponaria Molina, these natural glycosides can act as potent adjuvants. Their unique ability to stimulate Th1 immune responses and the production of cytotoxic T-cells makes them valuable vaccine adjuvant candidates for both human and veterinary purposes.
Exceptional standards in adjuvant manufacturing
Our aseptic process ensures we can deliver sterile aluminium according to GMP EudraLex Volume 4. We are one of the only companies worldwide to operate at such premium standards. Our Quality Management System is continually improved through established metrics.
A history of supporting vaccines
As a key player in adjuvant development since 1939, our adjuvants have consistently been featured in countless peer-reviewed papers. Our leading R&D capabilities demonstrate our determination to advance drug delivery systems and novel vaccine adjuvants to tackle even more pathogens.
Dedicated to your vaccine success
Developing and manufacturing vaccines is a costly challenge. Our team of experts are committed to helping you choose the right adjuvant for your needs. Save time and money by leveraging our decades worth of experience.
Download our adjuvants brochure here:
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Empowering the development of tomorrow's vaccines
