Immunostimulators

Prime effective immune responses

Elicit an amplified immune response through specific antigen presentation

Immunostimulators directly influence the immune response. Your selection of immunostimulators will direct the type of immune response. For example, whether the resultant response will be Th1, Th2, Th17 or T-cell mediated immunity.

As a result, they can play important roles in vaccine development by defining the type of immunity obtained (the immune fingerprint).

Explore our range of immunostimulators to fulfil your vaccine's immune correlates of protection.

Vaccines for a more sustainable future

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TLR agonists

Toll-like receptor (TLR) agonists are a class of proteins that play fundamental roles in innate immunity. Their discovery was honoured with the 2011 Nobel Prize. By mimicking the structure of pathogens, they can help stimulate the immune system. They are known as excellent adjuvant targets, having been part of several approved vaccines, such as for cervical cancer, shingles and Hepatitis B.

PHAD™

PHAD actúa como un agonista del receptor Toll-like 4 (TLR4) versátil y eficaz para activar las citocinas proinflamatorias y las células efectoras específicas de antígeno.

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3D-PHAD™

Puro, seguro y químicamente estable, 3D-PHAD estimula el sistema inmunitario a través de la activación de los receptores TLR4, lo que lleva a la producción de citoquinas proinflamatorias, células T CD4+...

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3D(6-acyl)-PHAD™

3D(6-acyl)-PHAD actúa como un inmunoestimulante altamente purificado ya que activa las células TLR4 para la inducción de citocinas proinflamatorias y células T.

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Saponins

Derived from the bark of Quillaja saponaria Molina, these natural glycosides can act as potent adjuvants. Their unique ability to stimulate Th1 immune responses and the production of cytotoxic T-cells makes them valuable vaccine adjuvant candidates for both human and veterinary purposes.

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QS 21

QS 21 es una saponina inmunoestimulante que actúa como un potente adyuvante de vacunas, estimulando las respuestas inmunitarias tanto celulares (Th1) como humorales (Th2).

Presentada

Quil-A™

Quil-A es un inmunoestimulante de saponina versátil y ampliamente utilizado como un potente adyuvante para aplicaciones veterinarias. Su uso en formulaciones destaca frente a patógenos intra y...

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Exceptional standards in adjuvant manufacturing

Our aseptic process ensures we can deliver sterile aluminium according to GMP EudraLex Volume 4. We are one of the only companies worldwide to operate at such premium standards. Our Quality Management System is continually improved through established metrics.

A history of supporting vaccines

As a key player in adjuvant development since 1939, our adjuvants have consistently been featured in countless peer-reviewed papers. Our leading R&D capabilities demonstrate our determination to advance drug delivery systems and novel vaccine adjuvants to tackle even more pathogens.

Dedicated to your vaccine success

Developing and manufacturing vaccines is a costly challenge. Our team of experts are committed to helping you choose the right adjuvant for your needs. Save time and money by leveraging our decades worth of experience.

Download our adjuvants brochure here:

Addressing the challenges of vaccine formulation

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