Visit Croda Pharma at AAPS Pharm Sci 2025!

great to meet you at AAPS PharmSci 360!

During AAPS PharmSci 360 Croda Pharma and Avanti Research highlighted our broad portfolio of excipients, ranging from Super Refined™ high purity excipients through to our expertise in lipid formulation.

Download our posters and presentation below!

POLYSORBATE HYDROLYSIS AND PROTEIN STABILITY: INVESTIGATING THE ROLE OF FREE FATTY ACID PARTICLES

Jinghan Li, Veronica F. Blanco, James Humphrey, Sreejit Menon, Stephen Rumbelow 973.9 KB

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High purity excipients and lipids in enabling advanced drug delivery

4.1 MB

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IMPROVING INTRANASAL NALOXONE DELIVERY USING EXCIPIENTS IN A TISSUE MODEL

Veronica F. Blanco, Garima Sinha, Christian Wells, Amy Druschitz, Kate McEvoy, Dharshana Padmakshan 529.0 KB

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High Purity Excipients and Lipids in Enabling Advanced Drug Delivery

This presentation examines the impact of excipient purity on formulation performance across small molecules, proteins, and nucleic acids. A high-purity dimethyl isosorbide enhances dermal permeation with improved stability in topical small molecule systems. Case studies reveal the role of polysorbate in mitigating surface-induced protein destabilization, and the advantage of high purity surfactants in improving drug stability. Purified surfactants also stabilize RNA-loaded lipid nanoparticles against physical stress by preventing particle leakage and aggregation.

Objectives:

Understand how excipient purity influences stability along with permeation and bioavailability in topical drug delivery.
Investigate the impact of surfactant purity on formulation stability and strategies to mitigate enzymatic degradation
Assess the role of purified surfactants in stabilizing LNP formulations for nucleic acid delivery upon mechanical shaking and freeze-thawing.

Jinghan Li, PhD

Applications Scientist, Croda Pharma

Poster Sessions

About Poster Session One:

Title: IMPROVING iNTRANASAL NALOXONE DELIVERY USING EXCIPIENTS IN A TISSUE MODEL

Poster number: M1330-08-50

Poster presentation: Monday, 1:30pm, Forum 8 on Monitor 50

Your presenter: Dr. Veronica Blanco

About Poster Session Two:

Title: POLYSORBATE HYDROLYSIS AND PROTEIN STABILITY: INVESTIGATING THE ROLE OF FREE FATTY ACID PARTICLES

Poster number: W1230-06-38

Poster presentation: Wednesday, 12:30pm, Forum 6 on Monitor 38

Your presenter: Dr. Jinghan Li

How we empower biologics delivery

Enabling breakthrough innovation

Dedicated to developing the next generation of excipients and delivery systems to empower biopharma

Access to specialist formulation support

Enabling over 250 on-going clinical projects targeting a range of therapeutic areas across biologics and small molecules

Focused scientific expertise

Leading the way with specialist knowledge and synthesis expertise in excipients, adjuvants and lipids

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great to meet you at AAPS PharmSci 360!

POLYSORBATE HYDROLYSIS AND PROTEIN STABILITY: INVESTIGATING THE ROLE OF FREE FATTY ACID PARTICLES

High purity excipients and lipids in enabling advanced drug delivery

IMPROVING INTRANASAL NALOXONE DELIVERY USING EXCIPIENTS IN A TISSUE MODEL

High Purity Excipients and Lipids in Enabling Advanced Drug Delivery

Poster Sessions

How we empower biologics delivery

Enabling breakthrough innovation

Access to specialist formulation support

Focused scientific expertise

Contact our experts today