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NEW product range Virodex™: Superior replacements to Triton™ X-100

Triton™ X-100 is used widely in the biopharmaceutical industry for virus inactivation and cell lysis applications. While the performance of Triton™ X-100 cannot be challenged, the detergent is associated with a number of disadvantages, with the product degrading to endocrine disrupting by-products, making it an aquatic reproductive toxin.₁ It is also included on the European Chemical Agency’s candidate list of substances of very high concern of the REACH regulation (Registration, Evaluation, Authorization and Restriction of Chemicals).₂

As a result, Triton™ X-100 alternatives have been developed₃, including our newly launched product range, Virodex™, addressing the industry need to find a suitable replacement for viral inactivation and/or cell lysis in their bioprocessing applications.

Watch our expert Dr. Kritika Bajaj discuss our product range in more detail and learn how Virodex™ could be the solution to your replacement requirement.

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Sustainable compendial grade GMP detergent substitutes for Triton™ X-100

Published on:

Monday 12th February 2024

1 Substance information ECHA. Available at: https://echa.europa.eu/substance-information/-/substanceinfo/100.123.919 (Accessed: 15 June 2023)

2 Candidate list of substances of very high concern for authorisation (2012) ECHA. Available at: https://echa.europa.eu/candidate-list-table/-/dislist/details/0b0236e1807db570 (Accessed: 19 May 2023)

3 Farcet, J-B. et al. (2019) Development of a Triton X-100 replacement for virus inactivation in biotechnology processes. Eng. Rep.. 1: e 12078.

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