Avanti™ DPPG
1,2-dipalmitoyl-sn-glycero-3-phospho-(1’-rac-glycerol), sodium salt (DPPG) is a kind of phosphoglyceride, which is also known as a glycerophospholipid. Phosphoglycerides consist of a three-carbon backbone of glycerol with two long-chain fatty acids esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C3 hydroxyl group of glycerol. They are found at high levels in all the membranes of cells and at low levels in fat stores.
PG can be found at higher concentrations (up to 11 percent of the total lipid content) within lung surfactant. Its presence in amniotic fluid is an indicator of fetal lung maturity and is the basis of clinical testing for fetal fitness.
Phosphoglycerides play a key role in cell signaling systems and serve as an anchor for proteins in cell membranes. 16:0 PG, specifically, has been used as a component in internal lipid standard mixture for matrix-assisted laser desorption/ionization (MALDI)-fourier-transform ion cyclotron resonance (FTICR)-mass spectrometry (MS) analysis.It has also been used to study the specificity of protein-lipid interactions in liposome flotation assays.