Our Span range of sorbitan esters are widely used as W/O emulsifiers and when used in combination with ethoxylated sorbitan esters (the Tween range) they contribute to the overall stability of O/W emulsions. Manipulation of the Span/Tween ratio produces emulsifying systems of various HLB values, allowing the emulsification of a wide range of oils and waxes. Span 85 is a liquid W/O emulsifier and O/W emulsion stabiliser used in nasal and metered dose inhalation dosage forms and as a dispersing agent in aerosols. Recommended topical usage levels of 0.5-5%.