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Tween™ 20 HP LSA

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Saturated free fatty acids have been associated with the formation of visible and sub-visible particles in cases where hydrolytic degradation of polysorbate 20 occurs. Tween™ 20 HP LSA is a highly purified polysorbate 20 that has been designed to provide functional equivalence as a surfactant whilst reducing the associated risk of visible and sub-visible particle formation in protein formulations. This has been achieved through a very highly controlled fatty acid distribution with lower content of long chain saturated fatty acids. 

Product details

Pharmacopoeia compliance

  • ChP
  • JP/JPE
  • Ph. Eur.
  • USP/NF

Chemical group

  • Polysorbate
  • Sorbitan ester

Administration route

  • Oral
  • Parenteral
  • Topical

Market application

  • Human pharmaceutical
  • Veterinary health


  • Emulsifier
  • Excipient
  • Nonionic surfactant
  • Wetting agent

Physical form

  • Clear yellow liquid