Virodex™ TXR-2

Macrogol 6 glycerol caprylocaprate (Ph. Eur.)

Virodex™ TXR-2 is a 40% biobased, nonionic surfactant for viral inactivation and cell lysis, meeting the needs of biopharmaceutical applications as an effective and safe replacement for the traditional detergent, Triton™ X-100. As a next-generation, sustainable detergent, Virodex™ TXR-2, along with its excellent biological compatibility, is recommended to be used in the efficient biomanufacturing of recombinant proteins such as monoclonal antibodies, as well as plasma-derived therapies, viral vector-based therapies and more. 

Key Benefits 
- 40% biobased, sustainable and REACH-compliant

- Meets cGMP EXCiPACT standards for the highest product quality in biopharmaceutical manufacturing  

- Compendial grade, in compliance with Ph. Eur. monograph 

- Known use of chemistry by industry for viral inactivation¹ 

- No risk of nitrosamine formation 

- Improved biologic quality and lower biomanufacturing risk, enabling faster speed to market 

- Equivalent virus inactivation and cell lysis characterization to Triton™ X-100, with better performance than three market alternatives

- Available pack sizes: 1 kg, 3 kg and 15 kg  

- Comes with additional COA testing: bacterial endotoxin, Total Aerobic Microbial Count (TAMC), and Total Yeast and Mould Count (TYMC) 

Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow.

¹Hunter, A. K. et al. Identification of compendial nonionic detergents for the replacement of Triton X‐100 in Bioprocessing. Biotechnology Progress 38, (2022).