Smart science to improve lives™
Abrir pesquisa Carrinho 0 Exibir cesta

Sustainable Squalene

Synthetic biology and purification excellence enable a highly purified alternative to shark-derived squalene.

View product

Non-animal derived, Sustainable Squalene in GMP quality 

Squalene is a critical ingredient in emulsion adjuvants used for seasonal and pandemic influenza vaccines. Its growing importance is underscored by its role in clinical development projects for prophylactic vaccines targeting tuberculosis, shingles, schistosomiasis, HIV, and other severe diseases—highlighting a strong and increasing demand for high-quality squalene. 

Ecological concerns with traditional squalene sources 

To date, the stringent purity requirements of the vaccine industry have largely been met by squalene sourced from liver oil extracted from deep-sea sharks. However, this approach poses significant ecological risks, threatening shark populations that are vital to marine ecosystems and global blue carbon balance. 

A sustainable, superior alternative to animal derived squalene 

Our Sustainable Squalene in GMP Quality leverages cutting-edge synthetic biology and fermentation technology to provide an innovative, environmentally friendly alternative. This advanced process yields pharmaceutical-grade squalene of highest purity, tailored for vaccine formulations. 

  • Superior Purity: The final purification step ensures that all test parameters and specification limits required by the European Pharmacopoeia (Ph. Eur.) monograph 2805 are met. With a purity of at least 99%, our Squalene meets the demanding specifications required by the vaccine industry. 

Squalene aligned with sustainability and global priorities 

The shift toward sustainable solutions aligns with global priorities for environmental conservation and stable supply chains, particularly in the production of lifesaving vaccines.

Key benefits include: 

  • Environmental Preservation: By eliminating reliance on shark-derived sources, our Sustainable Squalene helps conserve marine ecosystems and protect blue carbon reservoirs.
  • Low Environmental Impact: The raw materials used in our production process have minimal land-use impact. A comprehensive Product Carbon Footprint study has been conducted to evaluate its climate impact.
  • Supply Chain Stability: Fermentation-based production ensures a consistent, reliable, scalable, and ethical supply chain, critical for responding to seasonal and pandemic vaccine demands. 

Sustainable Squalene available for commercial vaccine production 

Our Sustainable Squalene, produced to GMP standards, is ready for use in the commercial manufacturing of vaccines - offering superior purity, ecological benefits, and a sustainable future for vaccine development. 

Find more information like this in our Frequently Asked Questions here.

ORDER YOUR SAMPLE TODAY!

 

Sustainable Squalene Featured

Sustainable Squalene

O Esqualeno, um triterpenóide, desempenha um papel fundamental nos adjuvantes de emulsão, sendo o óleo mais comumente empregado em adjuvantes de vacinas humanas. Os adjuvantes de emulsão contendo...

Non-shark derived, sustainably sourced Squalene

The squalene market is moving towards more sustainable solutions, helping contribute to global efforts to protect the planet

Superior purity

Our Squalene stands out on the market. It is at least 99% pure in line with stringent requirements of vaccine manufacturers

More robust and scalable supply chain

The use of sustainably sourced squalene helps us make progress towards a nature-positive supply chain

High-performing alternative

Demonstrated stability of emulsion adjuvants, with our non-shark derived Squalene
Learn more about how you can benefit from the supreme purity of our squalene. Contact us today to start the discussion.
female receiving injection of vaccine

Um histórico de apoio às vacinas

Atuando no desenvolvimento de adjuvantes desde 1939, nossos produtos têm sido frequentemente mencionados em inúmeros artigos revisados por especialistas. Nossas capacidades de pesquisa e desenvolvimento evidenciam nosso compromisso em impulsionar o mercado de Drug Delivery Systems e de novos adjuvantes de vacinas, visando combater uma variedade ainda maior de patógenos.
female in lab

Comprometidos com o sucesso da sua vacina

Desenvolver e fabricar vacinas é um desafio caro. Nossa equipe de especialistas técnicos está pronta para oferecer suporte na seleção do adjuvante de vacina mais adequado às suas necessidades. Utilize nossa expertise para economizar tempo e dinheiro durante esse processo.

Frequently asked questions

Download Croda Pharmas newest whitepaper: Vaccines for a more sustainable future

Vaccines for a more sustainable future

EXCLUSIVE WHITEPAPER

The vaccines of tomorrow revolve around sustainable supply chains and access to scalable commercial supplies that do not put undue pressure on the natural environment. It is our responsibility to future-proof vaccines by focusing on longevity in our processes. With combined global efforts, we can enhance the global health infrastructure, leading us to develop better vaccines against more diseases and supporting our preparedness for future outbreaks.

We believe that lobal collaborations are the cornerstone of creating a greener planet. Let's do all we can today, to generate a sustainable future we're proud of.

Download now!
indica campo obrigatório
Insira seu nome
Insira seu sobrenome
e-mail inválido
Precisamos do seu consentimento
Preencha a recaptcha e reenvie o formulário
1. https://www.mdpi.com/1424-8247/15/3/265#B16-pharmaceuticals-15-00265 
2.https://www.tandfonline.com/doi/full/10.1080/21645515.2017.1415684 
3. https://doi.org/10.1038/s41586-020-03173-9 
4. https://doi.org/10.1038/s41586-020-03173-9