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GMP grade polysorbates for Nucleic Acid Delivery

Polysorbates are non-ionic surfactants and emulsifiers commonly used in the pharmaceutical industry to promote API absorption and prevent the formation of aggregates and precipitation.

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Polysorbates

Polysorbates such as Tween are also commonly used to formulate lipid-based gene carriers. Playing a key role in these formulations as emulsifiers and stabilisers polysorbates also have an active role in the integration of DNA and therefore promote gene expression1.

We have a wide offering of compendial, high purity and Super Refined™ polysorbates to suit your formulation needs, explore our offering below! 

Tween_1_20_1_HP

Tween™ 20 HP

El Tween 20 HP supera los requisitos estándar de la monografía de Polisorbatos para obtener una versión con bajo contenido de peróxido y de humedad de Tween 20, diseñada para aplicaciones parenterales...

Tween_1_80_1_HP

Tween™ 80 HP

Tween 80 HP supera los requisitos estándar de la monografía de Polisorbatos para obtener una versión con bajo contenido de peróxido y de humedad de Tween 80, diseñada para aplicaciones parenterales y...

Super_1_Refined_1_Polysorbate_1_20

Super Refined™ Polysorbate 20

Los polisorbatos Super Refined se emplean para solubilizar y estabilizar los ingredientes activos más sensibles a través de diversas formas de dosificación, incluyendo inyectables y orales. El Super...

Super_1_Refined_1_Polysorbate_1_80

Super Refined™ Polysorbate 80

Los polisorbatos Super Refined se emplean para  solubilizar y estabilizar los ingredientes activos más sensibles a través de diversas formas de dosificación, incluyendo inyectables y orales. El Super...

Explore other GMP lipids:

Nucleic acid

Cationic lipids

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Nucleic acid

Phospholipids

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Nucleic acid

Functional lipids

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Nucleic acid

Sterols

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Nucleic acid

PEG lipids

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Why partner with us?

Support from concept to commercial

It starts with having the leading lipid technology experts in synthesis and formulation and approaching the discovery process in a collaborative nature, then having the expertise to transfer those learnings into a GMP manufacturing environment to support clinical development. And finally, having the commercial production capability to support launch and commercial supply.

Our full range of services include process chemistry, scale-up manufacturing, supply chain management with analytical and regulatory requirements. Our experienced staff of chemists and lipid analysts are ready to meet your development needs with pre-clinical through phase III and commercial launch, speak to one of our experts today!

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Lipid supporting services

CDMO cGMP manufacturing

CDMO project management from R&D through to commercialization. Contract manufacturing of proprietary lipid products.

Custom synthesis

Synthesis of research use materials for a variety of applications. Custom synthesis of reference standards or impurities.

Formulation

Development of a suitable formulation for lipid-based delivery systems. Custom lipid blends for use in delivery or diagnostic applications.
1. Huang, Y. et al. (2011) ‘Polysorbate cationic synthetic vesicle for gene delivery’, Journal of Biomedical Materials Research Part A, 96A(3), pp. 513–519. doi:10.1002/jbm.a.32999.