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Super Refined Poloxamer 188 for Biologic Formulation Stability

Poloxamer 188 is widely used in marketed biologics, including monoclonal antibodies, fusion proteins, and AAV-based gene therapies, where it is added to stabilise biologic molecules, minimise aggregation, and protect against interfacial stress. Super Refined™ Poloxamer 188 builds on this proven performance as a high purity surfactant from Croda Pharma’s trusted Super Refined™ range, engineered to enhance the stability and performance of the most sensitive parenteral formulations. Backed by extensive biologic formulation stability data, Super Refined™ Poloxamer 188 demonstrates robust performance and offers regulatory confidence as high purity, parenteral grade excipient—making it a reliable alternative to polysorbates in biologic formulations.

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