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Pharmaceutical excipients

Discover our excipients for use in cannabidiol (CBD) formulations

The demand for CBD in therapeutic products (or applications) is a growing trend, ease of administration and the rise in emphasis on self-sufficient, home-based healthcare is driving fast paced growth.

Cannabinoids can be used to aid treatment of ailments, such as anxiety, chronic and neurological pains, sleep disorders, stress, seizures, joint pain and inflammation, acne as well as nausea. They offer a wide variety of therapeutic benefits to the user and is non-toxic in nature with minimal side-effects.

Super Refined excipients

How is Croda meeting the trends using Super Refined™ excipient product solutions? 

Croda’s Super Refined excipients can save time and money in the form of faster development times, resulting in increased speed to market, a prolonged shelf-life of your final product, and finally lower development costs. Starting with a pure, high-quality pharmaceutical excipient to create your final product can lead to positive impacts from the start of the process through to finish; providing priceless benefits.

Discover Croda's Super Refined product solutions for CBD formulations.

Recommended products for oral delivery formulations 

  • Super Refined Sesame OilSuper Refined Corn Oil offer a low taste consumer benefit 
  • Super Refined Polysorbate 80 offers an extreme difference in taste compared to standard Polysorbate 80 

Our formulation experts can provide inspiration to support your formulation development.

It is estimated that around 80% of drugs are consumed orally. Orally administered medication can have an unpleasant bitter taste, before and after digestion; thus, causing poor consumer compliance.

Our Super Refined excipients offer many consumer benefits:

Oral delivery

  • Reduced taste impact
  • Low odour 
  • High quality
  • High purity 
  • Low colour

Topical delivery

  • Reduced skin irritation 
  • High quality
  • High purity 
  • Low colour

Recommended products for topical / transdermal formulations 

The skin is an excellent barrier, and that can make it challenging for topical drug delivery. 

  • Super Refined DMI improves spreading, enhances the delivery of actives 
  • Super Refined Oleic Acid improves drug delivery into the skin and reduces skin irritation 
  • Super Refined DEGEE enhances the permeation of poorly water-soluble API’s

Did you find what you are looking for? Our formulation experts can help to guide you in the right direction on which penetration enhancer to choose.

Get in touch to find out how we can help you overcome your CBD formulation challenges, whether it is poor stability or low permeability that you are struggling with, we are excited to help you understand and experience what the Super Refined solution has to offer.

vitamins and supplements

Oral

The development of oral drugs presents several challenges, including low solubility, instability of the formulation and ineffective delivery of the IFA. The selection of the correct oral excipient during the initial stage of development is a critical step in achieving the success of the formulation.

Mother carefully applying medical ointment

Topical

Our extensive experience in skin science has led to the development of innovative ingredients that enhance the efficacy and patient perception of topical pharmaceuticals. Our topical excipients include drug delivery systems, skin penetration enhancers, solubilisers, emulsifiers and emollients.

man using eye drop

Auricular, ophthalmic and nasal

Developing drugs to be delivered through the ophthalmic, auricular and nasal routes requires focus on essential factors, such as drug stability and endotoxin levels, which can impact the success of the formulation.

Purple capsule pills use in pharmaceutical manufacturing

SEDDS and SMEDDS

SEDDS and SMEDDS drug delivery systems are mixtures of oils, surfactants, solvents, and drug substance that rapidly and spontaneously form oil-in-water emulsions or microemulsions when introduced into aqueous phases under gentle agitation.

Penetration enhancer

Penetration enhancement

Our penetration enhancers deliver more of your active pharmaceutical ingredient (API) to the target location in order to improve product efficacy and lower API costs.

Excipients for use in cannabidiol formulations

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Super Refined™ Oils

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Get in touch to discover how we can help you