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ALC-0315

6-((2-hexyldecanoyl)oxy)-N-(6-((2-hexyldecanoyl)oxy)hexyl)-N-(4-hydroxybutyl)hexan-1-aminium

ALC-0315 is an ionizable cationic lipid used in combination with other lipids to form lipid nanoparticles (LNPs). 

Cationic lipids are used to complex negatively charged nucleic acid cargo and make up the center of an LNP delivery system.

image of ALC-0315 lipid nanoparticle structure, avanti polar lipids, croda pharma

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Nucleic Acid delivery croda pharma

ALC-0159

PEG (Polymer) - Lipid Conjugates
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DOPC

Phospholipid
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Cholesterol

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DSPC

Phospholipid
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DMPC

Phospholipid
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lipid nanoparticle cross section

A history of enabling drug delivery research

Avanti Polar Lipids develops high-purity, polar lipids that are being used as delivery systems for complex therapeutic drugs and in next-generation mRNA vaccines, with highly specialised lipids used in Lipid Nanoparticle (LNP) delivery technology, with a vast portfolio of phospholipids, cationic lipids, PEG lipids and sterols

Contract manufacturing of proprietary lipids and a formulations division to develop custom lipid-based drug delivery systems for a range of pharmaceutical applications

Expertise on development and scale-up and manufacturing of lipids under cGMP