ALC-0159
Methoxypolyethyleneglycoloxy(2000)-N,N-ditetradecylacetamide
ALC-0159 is a polyethylene glycol (PEG)-lipid conjugate also called a PEGylated lipid. ALC-0159 is a lipid excipient that can be used to form lipid nanoparticles (LNPs).
PEGylated lipids allow increased circulation times of LNP delivery systems due to their ability to circumvent systemic clearance.
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A history of enabling drug delivery research
Avanti Polar Lipids develops high-purity, polar lipids that are being used as delivery systems for complex therapeutic drugs and in next-generation mRNA vaccines, with highly specialised lipids used in Lipid Nanoparticle (LNP) delivery technology, with a vast portfolio of phospholipids, cationic lipids, PEG lipids and sterols
Contract manufacturing of proprietary lipids and a formulations division to develop custom lipid-based drug delivery systems for a range of pharmaceutical applications
Expertise on development and scale-up and manufacturing of lipids under cGMP